2024 P selectin mouse

P selectin mouse

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August undefined, 2024

WebP-selectin mediates the adhesion of neutrophils and monocytes to activated platelets and endothelial cells, mediates leukocyte rolling, and is involved in the migration of leukocytes … WebJul 27, 2011 · Homodimer; disulfide-linked. Interacts with P- and E-selectins, through their lectin/EGF domains. Interaction with P-selectin requires sialyl Lewis X glycan modification and tyrosine sulfation, probably on Tyr-54, for high affinity binding (By similarity). ... A0A0J9YV23_MOUSE: Selplg: 63: A0A0J9YTY7: A0A0J9YTY7_MOUSE: Selplg: 173: …

P-Selectin Mouse ELISA Kit - Invitrogen - Thermo Fisher Scientific

WebP-selectin functions as a cell adhesion molecule (CAM) on the surfaces of activated endothelial cells, which line the inner surface of blood vessels, and activated platelets. In unactivated endothelial cells, it is stored in granules called Weibel-Palade bodies. In unactivated platelets P-selectin is stored in α-granules . WebJan 13, 2011 · The aptamer:mouse P-selectin complex dissociated with a very slow off-rate such that a firm estimate cannot be determined but appears to be < 1 × 10 −4 /s (t 1/2 > 2 hours). These results demonstrate that ARC5690 binds mouse P-selectin with high specificity. Figure 3. how do you pronounce giusti

E-selectin-targeting lipid nanoparticles improve therapeutic …

WebMouse P-Selectin ELISA Kit (CD62P) (ab200014) is a single-wash 90 min sandwich ELISA designed for the quantitative measurement of P-Selectin (CD62P) protein in cit plasma, serum, cell culture supernatant, and cell culture extracts. It uses our proprietary SimpleStep ELISA® technology. Quantitate Mouse P-Selectin (CD62P) with 4.16 pg/ml ... WebDec 8, 2024 · P-selectin glycoprotein ligand-1 deficiency augments G-CSF induced myeloid cell mobilization. In p-selectin knock-out mice, several antiinflammatory cytokines were significantly increased following peripheral nerve injury. the presence of endogenous selectin ligands, particularly PSGL-1 on leukocytes, is required for cancer progression. WebThe Mouse P-selectin - IgG Fusion Protein is composed of the signal sequence, the lectin domain, the EGF-like repeat, and the first two complement-binding domains of mouse P … phone number barclays bank grimsby

BV421 Rat Anti-Mouse CD62P BD OptiBuild™

Recombinant Mouse P-Selectin/CD62P Fc Chimera …

WebP-Selectin, also known as GMP-140, LECAM-3, PADGEM, and CD62P, is a cell surface glycoprotein of the Selectin family and is expressed by activated platelets and endothelial cells (1-3). Mouse P-Selectin cDNA encodes a 768 amino acid (aa) type I transmembrane protein with a signal peptide, a large extracellular domain (ECD), a transmembrane ... WebWestern Blot analysis of P-Selectin (CD62P) in various cell lines using a P-Selectin (CD62P) Polyclonal antibody ( Product # PA5-120169) at a dilution of 1:1,000. 25 µg of lysate or protein were loaded into each lane. A blocking buffer of 3% nonfat dry milk in TBST was used. An HRP conjugated Goat Anti-Rabbit IgG (H+L) secondary antibody was ... how do you pronounce giveonWebE-Selectin [endothelial leukocyte adhesion molecule-1 (ELAM-1), CD62E] is transiently expressed on vascular endothelial cells in response to IL-1 beta and TNF-alpha. The human and rat proteins share approximately 67% amino acid sequence identity. The mouse and rat proteins share approximately 78% amino acid sequence identity. how do you pronounce glaive

"WebJun 4, 2009 · Plasma P-selectin has been shown to be elevated after stroke, and P-selectin deficiency and P-selectin antagonism protect from cerebral injury in models of MCAO. 23, … " - P selectin mouse

P selectin mouse

Mouse P-Selectin ELISA Kit (CD62P) (ab200014) Abcam

WebP-Selectin Protein, Mouse, Recombinant (His Tag): Synonyms CD62P Protein, Mouse; GMP-140 Protein, Mouse; Grmp Protein, Mouse; LECAM3 Protein, Mouse; PADGEM Protein, Mouse P-Selectin Background Information P selectin (SELP) is a 140kDa protein that is stored in the alpha-granules of platelets and Weibel-Palade bodies of endothelial cells. WebCD62P is a 140 kD type I transmembrane glycoprotein, also known as P-selectin, platelet activation-dependent granule membrane protein (PADGEM), and GMP-140. It is expressed on activated platelets, megakaryocytes, and endothelial cells.

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• P-Selectin at the U.S. National Library of Medicine Medical Subject Headings (MeSH) • Overview of all the structural information available in the PDB for UniProt: P16109 (Human P-selectin) at the PDBe-KB. • Overview of all the structural information available in the PDB for UniProt: Q01102 (Mouse P-selectin) at the PDBe-KB. WebThe Quantikine Mouse soluble P-Selectin (sP-Selectin) Immunoassay is a 4.5 hour solid phase ELISA designed to measure mouse sP-Selectin levels in cell culture supernates, serum, and EDTA plasma. It contains NS0-expressed recombinant mouse sP-Selectin and antibodies raised against the recombinant factor.

WebMouse Immunogen Thrombin activated rat platelets Formulation Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide. Preparation The antibody was purified by … WebP selectin (SELP) is a 140kDa protein that is stored in the alpha-granules of platelets and Weibel-Palade bodies of endothelial cells. SELP mediates rapid rolling of leukocyte rolling …

WebMeaning of P-Selectin. What does P-Selectin mean? Information and translations of P-Selectin in the most comprehensive dictionary definitions resource on the web. Login . WebCD62P is a 140 kD type I transmembrane glycoprotein, also known as P-selectin, platelet activation-dependent granule membrane protein (PADGEM), and GMP-140. It is expressed on activated platelets, megakaryocytes, and endothelial cells.

WebThe Mouse P-Selectin solid-phase sandwich ELISA (enzyme-linked immunosorbent assay) is designed to measure the amount of the target bound between a matched antibody pair. A target-specific antibody has been pre-coated in the wells of the supplied microplate. Samples, standards, or controls are then added into these wells and bind to the ...

WebP-selectin is a transmembrane adhesion receptor specific to platelets and endothelial cells. It has an N-terminal lectin domain that recognizes specific carbohydrate moieties on … phone number barclays bank lost cardWebJul 13, 2024 · Soluble P-selectin (sP-selectin) circulates in plasma of both humans and mice. In humans, a minor portion of sP-selectin is derived from alternative messenger RNA splicing that removes the exon encoding the transmembrane domain. 7-9 However, sP-selectin is primarily derived from proteolytic cleavage of the transmembrane protein, … how do you pronounce giusiWebMouse P-Selectin (GMP-140, LECAM-3, PADGEM, CD62P), a member of the Selectin family, is a cell surface glycoprotein expressed by activated platelets and endothelial cells. P-Selectin is translocated to the cell surface within minutes, from alpha granules of platelets or Weibel-Palade bodies of endothelial cells, following stimulation with ... phone number barclays customer serviceWebAntibodies that detect P-Selectin (CD62P) can be used in several scientific applications, including Flow Cytometry, Western Blot, Immunohistochemistry, Immunocytochemistry … how do you pronounce glenlivetWebApr 14, 2024 · The expression of P-selectin, the phosphorylation of myristoylated alanine-rich C kinase substrate by U46619 or ADP, and the activation of PAC-1 in platelets were inhibited by CSL. Nitric oxide production was increased by CSL in ADP- or U46619-treated human umbilical vein endothelial cells (HUVECs), although excessive endothelin-1 … how do you pronounce giulianoWebMouse P-Selectin ELISA Kit (CD62P) (ab200014) is a single-wash 90 min sandwich ELISA designed for the quantitative measurement of P-Selectin (CD62P) protein in cit plasma, … phone number bank of the west lakewoodWebApr 20, 2024 · P-Selectin Antibody (1 E 3) is a mouse monoclonal IgG2a, so for a secondary antibody you would want to use an anti-mouse IgG secondary antibody conjugated to either alkaline phosphatase (AP) or horseradish peroxidase (HRP), depending on what detection method being used. We would recommend our mouse IgG binding protein conjugated to … how do you pronounce gix