Lysosomal-associated membrane protein 1 (LAMP-1) also known as lysosome-associated membrane glycoprotein 1 and CD107a (Cluster of Differentiation 107a), is a protein that in humans is encoded by the LAMP1 gene. The human LAMP1 gene is located on the long arm (q) of chromosome 13 at region 3, … Skatīt vairāk Residing primarily across lysosomal membranes, these glycoproteins consist of a large, highly glycosylated end with N-linked carbon chains on the luminal side of the membrane, and a short C-terminal tail exposed to the Skatīt vairāk LAMP1 and LAMP2 glycoproteins comprise 50% of all lysosomal membrane proteins, and are thought to be responsible in part for maintaining lysosomal integrity, pH and catabolism. The expression of LAMP1 and LAMP2 glycoproteins are linked, as deficiencies in … Skatīt vairāk • Chang MH, Karageorgos LE, Meikle PJ (2003). "CD107a (LAMP-1) and CD107b (LAMP-2)". Journal of Biological Regulators and Homeostatic Agents. 16 (2): 147–51. Skatīt vairāk LAMP1 expression on the surface of tumor cells has been observed for a number of different cancer types, particularly in highly metastatic … Skatīt vairāk • Cluster of differentiation Skatīt vairāk • LAMP1+protein,+human at the U.S. National Library of Medicine Medical Subject Headings (MeSH) • PDBe-KB provides an overview of all the structure information available in the PDB for Human Lysosome-associated membrane glycoprotein 1 Skatīt vairāk TīmeklisLAMP1 分子背景 Lysosomal-associated membrane protein 1 (LAMP1) is also known as CD107a (Cluster of Differentiation 107a). LAMP1 / CD107a belongs to the LAMP …

Revisiting LAMP1 as a marker for degradative autophagy …

TīmeklisAll lanes : Anti-LAMP1 antibody - Lysosome Marker (ab24170) at 1 µg/ml Lane 1 : Jurkat (Human) Whole Cell Lysate Lane 2 : HEK293 (Human) Whole Cell Lysate … Tīmeklis2008. gada 23. sept. · Lysosomal membrane glycoprotein which plays an important role in lysosome biogenesis, autophagy, and cholesterol homeostasis ( By similarity ). Also plays an important role in NK-cells cytotoxicity ( PubMed: 23632890, PubMed: 2024921 ). Mechanistically, participates in cytotoxic granule movement to the cell surface and … easy welder to use for a beginner

Different localization of lysosomal-associated membrane protein 1 ...

TīmeklisLAMP1 is a heavily glycosylated membrane protein which contains a putative signal peptide, 18 sites for N-linked glycosylation, a single membrane-spanning segment and a short (11 amino acid) cytosolic tail. The LAMP proteins are involved in lysosome biogenesis and are required for fusion of lysosomes with phagosomes. Tīmeklislamp1 蛋白羧基末端暴露在细胞浆中，同时它含有一个将 lamp 蛋白靶向至溶酶体膜的酪氨酸分类基序 (4)。lamp1 和 lamp2 的蛋白序列有 37% 同源性。lamp1 和 lamp2 均 … Tīmeklis2024. gada 18. jūl. · LAMP1 (lysosomal associated membrane protein 1) and LAMP2 are distributed among autophagic and endolysosomal organelles. Despite … community\u0027s 7p