WebThe IncN2 plasmid backbone lacks sequence homology with IncN1 plasmids and cannot be typed using pMLST. To define and compare shared regions across groups of IncN1 plasmids, we identified genes common to all plasmid sequences using comparative sequence analysis (Figure 1a ). WebWe found that three genes had nominally significant interactions (p <0.05; Excel Table S9): cysteine-rich angiogenic inducer 61 (CYR61; also known as cellular communication …
Xinyi Huang - Research Technician - MRC-University of Glasgow …
WebOct 13, 2024 · Aim: To characterize a conjugative bla NDM-1-carrying plasmid pNDM-BTR from a clinical Escherichia coli isolate. Materials & methods: The complete nucleotide sequence of pNDM-BTR was determined using next-generation sequencing technology. Comparative genomic analysis of bla NDM-carrying IncN1 plasmids, including pNDM-BTR, … WebThe collection of IncN2 plasmids showed a backbone arrangement similar to the IncN1 and IncN3 collection, while nucleotide sequence homology showed limited similarity . … eyemart express lufkin texas
Emergence of a hybrid plasmid derived from IncN1-F33:A
WebApr 12, 2024 · IncN plasmids have been reported globally but are mainly prevalent in China and the United States. Of the 38 IncN1 plasmids reported in China (including the mainland and Taiwan, China), the major carbapenemase type was blaIMP (63.9%; 23/36), followed by blaNDM (19.4%; 7/36), and blaKPC (19.4%; 7/36). WebThis study dealt with sequencing and genomic dissection of two IncR:Inc pA1763-KPC :IncN1 multi-replicon plasmids p721005-KPC and p504051-KPC as well as an IncFII pHN7A8 :Inc pA1763-KPC :IncN1 plasmid pA3295-KPC. The backbone of each plasmid displayed a very complex chimera structure, with integration of several accessory modules composed … WebIt can mediate the fusion of IncN1-F33: A-:B-plasmids and phage-like plasmids carrying mcr-1. It can also mediate the emergence of the virulent, resistant, and highly transmissible... eyemart express midwest city ok